I am 43 years old. Diagnosed 3 years ago with Grade 3 Stage 3 lymphnode involvement I have received chemo, radiotherapy and have been on tamoxifen for the last 2 years and in receipt of zoladex injnctions due to tamoxifen bleeds. I saw my Oncologist last week and he wants me to start Arimidex. I have just been told I have lymphovascular invasion. What should I do take it or leave it?
There are other mild side effects, but frankly, Im not sure if theyre from the Arimidex, aging, menopause, long-lasting chemo effects, or what! Theyre all just part of the cancer aftermath, and you learn to live with whatever youre feeling, because the key word is LIVE.
Bones ache from top of head to bottom of feet. Arm, hip, toe fractures and possible lower left rib fracture, Itching body Hair thinning, headaches, mind going hazy, Feel 90 years sleep at night, Fall asleep sitting in chairs with no arms find myself on floor usually with a fracture. Fingers are swollen, fingers going different directions. Knees hurt. I am tired of being a guinea pig for Arimidex. My oncologist says maybe we can do some testing down the road. Sorry I am done testing for anyone I am finished. Terrible weight gain of 40 pounds.
It is very common for Selective Estrogen Receptor Modulators (SERM'S) to be thrown in the same anti-estrogen category as Arimidex and other AI'S but this is far from correct. SERM'S such as Tamoxifen Citrate (Nolvadex) and Clomiphene Citrate (Clomid) do not inhibit the aromatase process in the body; they do not actively reduce the total amount of estrogen in the body. SERM'S such as Nolvadex or Clomid simply block estrogen from binding to certain receptors in the body and this can be a very useful tool; however, as you can see it is not nearly as strong since it has no reducing capability. Even so, SERM'S in the same light as AI'S actively increase or stimulate natural testosterone production and for this reason are commonly used during what is known as the Post Cycle Therapy (PCT) plan. Yes, both SERM'S and AI'S can be used for PCT purposes, the PCT purpose being largely to return testosterone production back to normal after it has been diminished through anabolic steroid use. However, we do not recommend AI'S for PCT therapy, even though they will increase testosterone greatly we prefer SERM'S for this purpose for one simple reason. During the PCT process we are not simply trying to increase testosterone but to normalize our entire hormonal production. As AI'S greatly reduce estrogen, a much needed hormone in the human body, we prefer SERM'S over AI'S to fulfill this purpose.
Arimidex not only lowers circulating estrogen but it also increases LH and FSH concentrations in addition to increasing testosterone by about 58% in men. In one study elderly men with mild hypogonadism were administered 1mg daily of Arimidex for 12 weeks. This treatment normalized serum testosterone levels in those men without adversely affecting lipids, inflammatory markers of cardiovascular risk or insulin resistance.
This study also looked at people taking tamoxifen for 5 years, or those who take it for several than switch to Arimidex. A "Censored" Version of results that wasn'T official showed no advantage in cancer recurrence for Arimidex but a slight improvement in overall survival.
Tommyticklemouse - as Lemoncake says, you can have Arimidex if you have not had your menopause if you take the Zoladex as well which shuts down ovarian function ie makes you post menopausal. I don'T think it is the first line of treatment in pre menopausal women because there are a lot of downsides to a premature menopause. In my case it is because Tamoxifen was not effective and I had a new primary 6 months after a mastectomy.
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Thank you for your input Terri. I have looked at the drugs online and they do seem comparable so maybe I will switch and see what happens until my next oncology appt in May. One of my concerns is that I'D never heard of Aromasin before - only the main 3 Tamoxifen, Femara and Arimidex- so am a little hesitant to switch but I must say I am seeing relief in my joint pain. I DO however have arthritis in all my joints which causes pain I have to live with, but I think now that the Femara was increasing the pain plus causing more muscle pain as well. Only time will tell. My thanks again for your help.arimidex 1mg, arimidex generic, arimidex online, order arimidex, arimidex buy online, where to buy arimidex online, drug arimidex, buy liquid arimidex, arimidex prices, arimidex cheap, aromasin vs arimidex, arimidex men, tamoxifen versus arimidex, arimidex patient assistance, arimidex patent expiration, nolvadex or arimidex, what is arimidex used for men, arimidex and arthritis